Nguan Soon Tan Selected Research

Neoplasm Metastasis (Metastasis)

4/2021	PPARs and Tumor Microenvironment: The Emerging Roles of the Metabolic Master Regulators in Tumor Stromal-Epithelial Crosstalk and Carcinogenesis.
1/2019	Exploiting vulnerabilities of cancer by targeting nuclear receptors of stromal cells in tumor microenvironment.
1/2019	Epithelial-mesenchymal transition of cancer cells using bioengineered hybrid scaffold composed of hydrogel/3D-fibrous framework.
1/2019	Reactive oxygen species: a volatile driver of field cancerization and metastasis.
10/2018	Targeting metabolic flexibility via angiopoietin-like 4 protein sensitizes metastatic cancer cells to chemotherapy drugs.
1/2012	Matricellular proteins: a sticky affair with cancers.
10/2011	ANGPTL4 modulates vascular junction integrity by integrin signaling and disruption of intercellular VE-cadherin and claudin-5 clusters.
12/2010	Angiopoietin-like 4 interacts with integrins beta1 and beta5 to modulate keratinocyte migration.

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Nguan Soon Tan Research Topics

Disease

37	Neoplasms (Cancer) 02/2024 - 01/2003
23	Wounds and Injuries (Trauma) 02/2024 - 10/2002
15	Inflammation (Inflammations) 01/2023 - 02/2004
8	Neoplasm Metastasis (Metastasis) 04/2021 - 12/2010
8	Infections 10/2019 - 03/2006
7	Spontaneous Abortion (Miscarriage) 01/2021 - 01/2015
6	Threatened Abortion 01/2020 - 01/2015
5	Obesity 11/2023 - 01/2003
5	Non-alcoholic Fatty Liver Disease 12/2022 - 01/2018
4	Breast Neoplasms (Breast Cancer) 01/2022 - 01/2019
3	Melanoma (Melanoma, Malignant) 02/2024 - 12/2014
3	Asthma (Bronchial Asthma) 11/2023 - 09/2016
3	Cicatrix (Scar) 01/2023 - 01/2017
3	Type 2 Diabetes Mellitus (MODY) 01/2023 - 02/2011
3	Fibrosis (Cirrhosis) 07/2022 - 01/2018
3	Hypoxia (Hypoxemia) 01/2021 - 08/2004
3	Carcinogenesis 01/2020 - 06/2012
2	Glioblastoma (Glioblastoma Multiforme) 02/2024 - 02/2016
2	Glioma (Gliomas) 02/2024 - 01/2019
2	Disease Progression 07/2021 - 01/2021
2	Dyslipidemias (Dyslipidemia) 10/2019 - 01/2017
2	Atherosclerosis 01/2017 - 07/2013
2	Acute-Phase Reaction 01/2017 - 12/2010
2	Insulin Resistance 06/2012 - 02/2011
2	Hepatocellular Carcinoma (Hepatoma) 05/2007 - 08/2004
1	Growth Disorders 11/2023
1	Chronic Obstructive Pulmonary Disease (COPD) 11/2023
1	Emphysema 11/2023
1	Immune System Diseases (Immune Disorders) 11/2023
1	Liposarcoma 09/2023

Drug/Important Bio-Agent (IBA)

14	AngiopoietinsIBA 11/2023 - 10/2010
13	Proteins (Proteins, Gene)FDA Link 01/2023 - 12/2010
11	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 06/2020 - 01/2003
9	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 06/2020 - 05/2005
9	PPAR-betaIBA 03/2009 - 10/2002
7	Progesterone FDA LinkGeneric 01/2021 - 01/2015
7	LipidsIBA 10/2019 - 10/2010
6	HydrogelsIBA 02/2024 - 10/2016
5	CollagenIBA 07/2022 - 04/2012
5	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020 - 06/2012
5	IntegrinsIBA 09/2014 - 12/2010
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 12/2017
4	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 10/2010
3	Phosphotransferases (Kinase)IBA 02/2024 - 01/2019
3	Messenger RNA (mRNA)IBA 11/2023 - 08/2004
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2023 - 12/2016
3	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2019
3	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022 - 04/2014
3	Triglycerides (Triacylglycerol)IBA 01/2017 - 12/2010
3	Fibrinogen (Factor I)FDA Link 06/2012 - 10/2011
3	PPAR alphaIBA 05/2007 - 05/2004
2	Temozolomide (Temodar)FDA LinkGeneric 02/2024 - 01/2021
2	Carbapenems (Carbapenem Antibiotics)IBA 02/2024 - 06/2018
2	AntibodiesIBA 11/2023 - 01/2019
2	Transcription Factors (Transcription Factor)IBA 01/2023 - 06/2020
2	Cysteine (L-Cysteine)FDA Link 07/2022 - 01/2018
2	ChemokinesIBA 01/2022 - 01/2017
2	Cisplatin (Platino)FDA LinkGeneric 11/2021 - 10/2018
2	Biocompatible Materials (Biomaterials)IBA 01/2021 - 09/2015
2	CytokinesIBA 01/2021 - 03/2020
2	PolyaminesIBA 10/2020 - 12/2014
2	GW 501516IBA 03/2020 - 01/2015
2	blocking factorIBA 01/2020 - 01/2015
2	Neutralizing AntibodiesIBA 01/2020 - 01/2019
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2019 - 11/2017
2	AdipokinesIBA 01/2018 - 08/2004
2	Fatty Acids (Saturated Fatty Acids)IBA 12/2017 - 12/2010
2	CyclodextrinsIBA 10/2017 - 04/2014
2	Conditioned Culture MediaIBA 01/2017 - 12/2014
2	LigandsIBA 01/2017 - 02/2004
2	CatalaseIBA 01/2017 - 01/2015
2	Transforming Growth Factors (Transforming Growth Factor)IBA 12/2014 - 05/2005
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 09/2014 - 03/2006
2	FicolinsIBA 11/2013 - 12/2010
1	binimetinibIBA 02/2024
1	ralimetinibIBA 02/2024
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 02/2024
1	Protein Kinases (Protein Kinase)IBA 02/2024
1	Antisense OligonucleotidesIBA 11/2023
1	Toll-Like Receptor 7IBA 11/2023
1	Monoclonal AntibodiesIBA 11/2023
1	Cromolyn Sodium (Cromoglicic Acid)FDA LinkGeneric 11/2023
1	SmokeIBA 11/2023
1	Mast Cell StabilizersIBA 11/2023
1	Imiquimod (Aldara)FDA LinkGeneric 11/2023
1	AntigensIBA 11/2023
1	LipopolysaccharidesIBA 11/2023
1	Environmental Pollutants (Pollutants, Environmental)IBA 11/2023
1	bisphenol AIBA 11/2023
1	abemaciclibIBA 09/2023
1	Peptide Hydrolases (Proteases)FDA Link 01/2023
1	Silk FDA Link 01/2023
1	CryogelsIBA 01/2023
1	Small Interfering RNA (siRNA)IBA 07/2022
1	Hyaluronic Acid (Hyaluronan)IBA 07/2022
1	GelatinIBA 07/2022

Therapy/Procedure

13	Therapeutics 09/2023 - 09/2014
5	Precision Medicine 03/2023 - 01/2019
5	Drug Therapy (Chemotherapy) 12/2022 - 10/2014
2	Magnetic Field Therapy 01/2022 - 01/2021